This book provides fundamental principles, terminology, mechanisms, methods, types and applications of unit operation in downstream processing of various fields, ranging from engineering, technology, pure sciences and applied sciences. The discussion revolves around the principle of unit operations such as filtration, coagulation and flocculation, centrifugation, cell disruption, adsorption, chromatography, distillation, crystallization and drying. This book is designed to serve as a reference book for students, researchers, professionals and others who work in the processing industries.